Publikacje
Urine iodine excretion in patients with papillary thyroid cancer evaluation of the relationship with the presence of BRAF mutation
„Celik M., Guldiken S., Salt S.A., Bulbul B.Y., Kucukarda A., Can N., Tastekin E., Sezer A., Sut N., Tugrul A., Gurkan H., Tozkir H., Demirkan B. 2020. Urine iodine excretion in patients with papillary thyroid cancer evaluation of the relationship with the presence of BRAF mutation. J. Elem., 25(3): 1019 – 1028. DOI: 10.5601/jelem.2020.25.1.1984”
DOI: 10.5601/jelem.2020.25.1.1984
Iodine is an essential element for the production of thyroid hormones. In recent years, it has been suggested that excessive consumption of iodine may play a role in the pathogenesis of papillary thyroid cancer (PTC). In addition, studies have suggested that high iodine consumption is an important risk factor for the formation of a BRAF mutation in the thyroid gland. A prospectively designed study included 132 cases scheduled for thyroidectomy for various reasons. Urine iodine levels of all patients were examined before the operation. The iodine excretion levels of the patients were grouped according to the median urinary iodine concentration determined in community screenings (those with
Słowa kluczowe: papillary thyroid cancer, BRAF mutation, urine iodine excretion
